Augmenting MNK1/2 activation by c-FMS proteolysis promotes osteoclastogenesis and arthritic bone erosion

Osteoclasts are bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathological bone erosion. Macrophage colony stimulating factor (M-CSF) is abundant in rheumatoid arthritis (RA). However, the role of M-CSF in arthritic bone erosion is not completely understood. Her...

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Detalles Bibliográficos
Autores principales: Mun, Se Hwan, Bae, Seyeon, Zeng, Steven, Oh, Brian, Chai, Carmen, Kim, Matthew Jundong, Kim, Haemin, Kalliolias, George, Dahia, Chitra Lekha, Oh, Younseo, Kim, Tae-Hwan, Ji, Jong Dae, Park-Min, Kyung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528869/
https://www.ncbi.nlm.nih.gov/pubmed/34671034
http://dx.doi.org/10.1038/s41413-021-00162-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528869/
https://www.ncbi.nlm.nih.gov/pubmed/34671034
http://dx.doi.org/10.1038/s41413-021-00162-0

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