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Augmenting MNK1/2 activation by c-FMS proteolysis promotes osteoclastogenesis and arthritic bone erosion

Osteoclasts are bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathological bone erosion. Macrophage colony stimulating factor (M-CSF) is abundant in rheumatoid arthritis (RA). However, the role of M-CSF in arthritic bone erosion is not completely understood. Her...

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Detalles Bibliográficos
Autores principales:	Mun, Se Hwan, Bae, Seyeon, Zeng, Steven, Oh, Brian, Chai, Carmen, Kim, Matthew Jundong, Kim, Haemin, Kalliolias, George, Dahia, Chitra Lekha, Oh, Younseo, Kim, Tae-Hwan, Ji, Jong Dae, Park-Min, Kyung-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528869/ https://www.ncbi.nlm.nih.gov/pubmed/34671034 http://dx.doi.org/10.1038/s41413-021-00162-0

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