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LncRNA SNHG17 interacts with LRPPRC to stabilize c-Myc protein and promote G1/S transition and cell proliferation

Oncogenic c-Myc is a master regulator of G1/S transition. Long non-coding RNAs (lncRNAs) emerge as new regulators of various cell activities. Here, we found that lncRNA SnoRNA Host Gene 17 (SNHG17) was elevated at the early G1-phase of cell cycle. Both gain- and loss-of function studies disclosed th...

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Detalles Bibliográficos
Autores principales: Liu, Jin-Yu, Chen, Ya-Jing, Feng, Huan-Hui, Chen, Zhan-Li, Wang, Yun-Long, Yang, Jin-E, Zhuang, Shi-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528917/
https://www.ncbi.nlm.nih.gov/pubmed/34671012
http://dx.doi.org/10.1038/s41419-021-04238-x