Cargando…

ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppression

Tumors exhibit a variety of strategies to dampen antitumor immune responses. With an aim to identify factors that are secreted from tumor cells, we performed an unbiased mass spectrometry-based secretome analysis in lung cancer cells. Interleukin-6 (IL-6) has been identified as a prominent factor se...

Descripción completa

Detalles Bibliográficos
Autores principales: Riegel, Kristina, Yurugi, Hajime, Schlöder, Janine, Jonuleit, Helmut, Kaulich, Manuel, Kirschner, Friederike, Arnold-Schild, Danielle, Tenzer, Stefan, Schild, Hansjörg, Rajalingam, Krishnaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528934/
https://www.ncbi.nlm.nih.gov/pubmed/34671021
http://dx.doi.org/10.1038/s41419-021-04257-8