Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies

Background/Aim: Host defense peptides (HDPs) have the potential to provide a novel solution to antimicrobial resistance (AMR) in view of their unique and broad-spectrum antimicrobial activities. We had recently developed a novel hybrid HDP based on LL-37 and human beta-defensin-2, named CaD23, which...

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Detalles Bibliográficos
Autores principales: Ting, Darren Shu Jeng, Li, Jianguo, Verma, Chandra S., Goh, Eunice T. L., Nubile, Mario, Mastropasqua, Leonardo, Said, Dalia G., Beuerman, Roger W., Lakshminarayanan, Rajamani, Mohammed, Imran, Dua, Harminder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528955/
https://www.ncbi.nlm.nih.gov/pubmed/34690770
http://dx.doi.org/10.3389/fphar.2021.731499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528955/
https://www.ncbi.nlm.nih.gov/pubmed/34690770
http://dx.doi.org/10.3389/fphar.2021.731499

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