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Effects of Cytochrome P450 and Transporter Polymorphisms on the Bioavailability and Safety of Dutasteride and Tamsulosin

Dutasteride and tamsulosin are one of the first-line combination therapies for the management of benign prostatic hyperplasia (BPH). Despite being more effective than monotherapies, they produce frequent adverse drug reactions (ADRs). Institutions such as Food and Drug Administration and European Me...

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Detalles Bibliográficos
Autores principales: Villapalos-García, Gonzalo, Zubiaur, Pablo, Navares-Gómez, Marcos, Saiz-Rodríguez, Miriam, Mejía-Abril, Gina, Martín-Vílchez, Samuel, Román, Manuel, Ochoa, Dolores, Abad-Santos, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529037/
https://www.ncbi.nlm.nih.gov/pubmed/34690761
http://dx.doi.org/10.3389/fphar.2021.718281