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A CRISPR-Cas12b–Based Platform for Ultrasensitive, Rapid, and Highly Specific Detection of Hepatitis B Virus Genotypes B and C in Clinical Application

Hepatitis B virus (HBV) is one of the most dangerous and prevalent agents that causes acute and chronic liver diseases in humans. Genotyping plays an important role in determining clinical outcomes and response to antiviral treatment in HBV–infected patients. Here, we first devised a CRISPR–based te...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Tan, Yan, Wang, Shuoshi, Wu, Xueli, Liu, Rui, Yang, Xinggui, Wang, Yi, Tai, Jun, Li, Shijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529042/
https://www.ncbi.nlm.nih.gov/pubmed/34692662
http://dx.doi.org/10.3389/fbioe.2021.743322