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Immunomodulatory Effects of Perioperative Dexmedetomidine in Ovarian Cancer: An In Vitro and Xenograft Mouse Model Study

BACKGROUND: The surgical stress response (SSR) causes immunosuppression which may cause residual tumor growth and micrometastasis after cancer surgery. We investigated whether dexmedetomidine affects cancer cell behavior and immune function in an ovarian cancer xenograft mouse model. METHODS: The ef...

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Detalles Bibliográficos
Autores principales: Shin, Seokyung, Kim, Ki Jun, Hwang, Hye Jeong, Noh, Sewon, Oh, Ju Eun, Yoo, Young-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529066/
https://www.ncbi.nlm.nih.gov/pubmed/34692497
http://dx.doi.org/10.3389/fonc.2021.722743