Cargando…

Immunomodulatory Effects of Perioperative Dexmedetomidine in Ovarian Cancer: An In Vitro and Xenograft Mouse Model Study

BACKGROUND: The surgical stress response (SSR) causes immunosuppression which may cause residual tumor growth and micrometastasis after cancer surgery. We investigated whether dexmedetomidine affects cancer cell behavior and immune function in an ovarian cancer xenograft mouse model. METHODS: The ef...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Seokyung, Kim, Ki Jun, Hwang, Hye Jeong, Noh, Sewon, Oh, Ju Eun, Yoo, Young-Chul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529066/ https://www.ncbi.nlm.nih.gov/pubmed/34692497 http://dx.doi.org/10.3389/fonc.2021.722743

Ejemplares similares

Effects of Perioperative Dexmedetomidine on Immunomodulation in Uterine Cancer Surgery: A Randomized, Controlled Trial
por: Cho, Jin Sun, et al.
Publicado: (2021)

Identification for antitumor effects of tramadol in a xenograft mouse model using orthotopic breast cancer cells
por: Kim, Myoung Hwa, et al.
Publicado: (2021)

Immunomodulatory effect of splenectomy in lung cancer mouse xenograft models receiving radiation therapy
por: Kim, Yeeun, et al.
Publicado: (2022)

The effects of perioperative dexmedetomidine infusion on hemodynamic stability during laparoscopic adrenalectomy for pheochromocytoma: a randomized study
por: Kim, Youngwon, et al.
Publicado: (2023)

Patient-Derived Xenograft Models to Improve Targeted Therapy in Epithelial Ovarian Cancer Treatment
por: Scott, Clare L., et al.
Publicado: (2013)

In situ Metabolic Profiling of Ovarian Cancer Tumor Xenografts: A Digital Pathology Approach
por: Piga, Ilaria, et al.
Publicado: (2020)

Patient-Derived Xenografts Are a Reliable Preclinical Model for the Personalized Treatment of Epithelial Ovarian Cancer
por: Chen, Jiayu, et al.
Publicado: (2021)

Immunomodulatory action of the DNA methyltransferase inhibitor SGI-110 in epithelial ovarian cancer cells and xenografts
por: Srivastava, Pragya, et al.
Publicado: (2015)

In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma
por: Whitehouse, Jacqueline P., et al.
Publicado: (2023)

Feasibility of Single-Port Access (SPA) Laparoscopy for Large Ovarian Tumor Suspected to Be Borderline Ovarian Tumor
por: Kang, Jun-Hyeok, et al.
Publicado: (2020)

Ovarian Tumor Attachment, Invasion, and Vascularization Reflect Unique Microenvironments in the Peritoneum: Insights from Xenograft and Mathematical Models
por: Steinkamp, Mara P., et al.
Publicado: (2013)

Short-Term Circulating Tumor Cell Dynamics in Mouse Xenograft Models and Implications for Liquid Biopsy
por: Williams, Amber L., et al.
Publicado: (2020)

Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies
por: Heo, Eun Jin, et al.
Publicado: (2017)

Effect of dexmedetomidine anesthesia on perioperative levels of TNF-α and IL-6 in patients with ovarian cancer
por: Liu, Maodong, et al.
Publicado: (2019)

Role of reactive thrombocytosis after primary cytoreductive surgery in advanced ovarian cancer
por: Kim, Myeong-Seon, et al.
Publicado: (2022)

Effects of dexmedetomidine on A549 non-small cell lung cancer growth in a clinically relevant surgical xenograft model
por: Jun, Ji Hae, et al.
Publicado: (2023)

Autologous humanized mouse models to study combination and single-agent immunotherapy for colorectal cancer patient-derived xenografts
por: Kanikarla Marie, Preeti, et al.
Publicado: (2022)

Perioperative Dexmedetomidine Improves Outcomes of Kidney Transplant
por: Chen, Jun, et al.
Publicado: (2020)

Rectosigmoid sparing en bloc pelvic resection for fixed ovarian tumors: Surgical technique and perioperative and oncologic outcomes
por: Shan, Ying, et al.
Publicado: (2022)

Perioperative lidocaine and dexmedetomidine intravenous infusion reduce the serum levels of NETs and biomarkers of tumor metastasis in lung cancer patients: A prospective, single-center, double-blinded, randomized clinical trial
por: Ren, Baiqing, et al.
Publicado: (2023)

Immunogenic Cell Death and Immunomodulatory Effects of Cabozantinib
por: Scirocchi, Fabio, et al.
Publicado: (2021)

Interval debulking surgery with or without hyperthermic intraperitoneal chemotherapy in advanced-stage ovarian cancer: Single-institution cohort study
por: Lee, Yong Jae, et al.
Publicado: (2022)

Development of a Mouse Model of Menopausal Ovarian Cancer
por: Smith, Elizabeth R., et al.
Publicado: (2014)

The Ever-Expanding Immunomodulatory Role of Calreticulin in Cancer Immunity
por: de Bruyn, Marco, et al.
Publicado: (2015)

Harnessing the Immunomodulatory Effects of Radiation in Urinary Bladder Cancer
por: Abbas, Waseem, et al.
Publicado: (2019)

The Influence of Perioperative Dexmedetomidine on Patients Undergoing Cardiac Surgery: A Meta-Analysis
por: Geng, Jun, et al.
Publicado: (2016)

Impact of perioperative red blood cell transfusion, anemia of cancer and global health status on the prognosis of elderly patients with endometrial and ovarian cancer
por: Anic, Katharina, et al.
Publicado: (2022)

Immunomodulatory Activity of Red Ginseng against Influenza A Virus Infection
por: Lee, Jong Seok, et al.
Publicado: (2014)

Characterization of orthotopic xenograft tumor of glioma stem cells (GSCs) on MRI, PET and immunohistochemical staining
por: Liu, Yufei, et al.
Publicado: (2022)

The impact of sMICA/sMICB on immunochemotherapy outcomes in newly diagnosed diffuse large B-cell lymphoma
por: Yoon, Sang Eun, et al.
Publicado: (2023)

Identification of Circular RNA-Based Immunomodulatory Networks in Colorectal Cancer
por: Feng, Zongfeng, et al.
Publicado: (2022)

Tumor and microenvironmental mechanisms of resistance to immunomodulatory drugs in multiple myeloma
por: Chen, Lucia Y., et al.
Publicado: (2022)

The impact of Enhanced Recovery after Surgery (ERAS) pathways with regard to perioperative outcome in patients with ovarian cancer
por: Reuter, Susanne, et al.
Publicado: (2021)

Recent Technological Advances in Using Mouse Models to Study Ovarian Cancer
por: House, Carrie Danielle, et al.
Publicado: (2014)

Editorial: Perioperative management and cancer outcome
por: Tao, Yiying, et al.
Publicado: (2023)

Establishing and Maintaining an Extensive Library of Patient-Derived Xenograft Models
por: Mattar, Marissa, et al.
Publicado: (2018)

Immunomodulatory role of azithromycin: Potential applications to radiation-induced lung injury
por: Yan, Yujie, et al.
Publicado: (2023)

Perioperative Dexmedetomidine for outpatient cataract surgery: a systematic review
por: Jones, James Harvey, et al.
Publicado: (2020)

Adoption of Dexmedetomidine in Different Doses at Different Timing in Perioperative Patients
por: Xie, Jing, et al.
Publicado: (2022)

Vascularization, Oxygenation, and the Effect of Sunitinib Treatment in Pancreatic Ductal Adenocarcinoma Xenografts
por: Gaustad, Jon-Vidar, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vo194jbcbq0ggkegtnli3vdnhm