Cryptococcus neoformans Cda1 and Cda2 coordinate deacetylation of chitin during infection to control fungal virulence

Chitosan, a deacetylated form of chitin, is required for the virulence of Cryptococcus neoformans. There are three chitin deacetylase genes (CDA) that are essential for chitosan production, and deletion of all three genes results in the absence of chitosan, loss of virulence, and induction of a prot...

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Detalles Bibliográficos
Autores principales: Upadhya, Rajendra, Lam, Woei C., Hole, Camaron R., Parchment, Danealle, Lee, Chrono K., Specht, Charles A., Levitz, Stuart M., Lodge, Jennifer K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529172/
https://www.ncbi.nlm.nih.gov/pubmed/34712865
http://dx.doi.org/10.1016/j.tcsw.2021.100066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529172/
https://www.ncbi.nlm.nih.gov/pubmed/34712865
http://dx.doi.org/10.1016/j.tcsw.2021.100066

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