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Cryptococcus neoformans Cda1 and Cda2 coordinate deacetylation of chitin during infection to control fungal virulence
Chitosan, a deacetylated form of chitin, is required for the virulence of Cryptococcus neoformans. There are three chitin deacetylase genes (CDA) that are essential for chitosan production, and deletion of all three genes results in the absence of chitosan, loss of virulence, and induction of a prot...
Autores principales: | Upadhya, Rajendra, Lam, Woei C., Hole, Camaron R., Parchment, Danealle, Lee, Chrono K., Specht, Charles A., Levitz, Stuart M., Lodge, Jennifer K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529172/ https://www.ncbi.nlm.nih.gov/pubmed/34712865 http://dx.doi.org/10.1016/j.tcsw.2021.100066 |
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