The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (Naja Species) Venoms

African spitting cobras are unique among cobras for their potent anticoagulant venom activity arising from strong inhibition of Factor Xa. This anticoagulant effect is exerted by venom phospholipase A(2) (Group I PLA(2)) toxins whose activity contributes to the lethality of these species. This antic...

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Detalles Bibliográficos
Autores principales: Chowdhury, Abhinandan, Lewin, Matthew R., Zdenek, Christina N., Carter, Rebecca, Fry, Bryan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529177/
https://www.ncbi.nlm.nih.gov/pubmed/34691069
http://dx.doi.org/10.3389/fimmu.2021.752442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529177/
https://www.ncbi.nlm.nih.gov/pubmed/34691069
http://dx.doi.org/10.3389/fimmu.2021.752442

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