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The Relative Efficacy of Chemically Diverse Small-Molecule Enzyme-Inhibitors Against Anticoagulant Activities of African Spitting Cobra (Naja Species) Venoms
African spitting cobras are unique among cobras for their potent anticoagulant venom activity arising from strong inhibition of Factor Xa. This anticoagulant effect is exerted by venom phospholipase A(2) (Group I PLA(2)) toxins whose activity contributes to the lethality of these species. This antic...
Autores principales: | Chowdhury, Abhinandan, Lewin, Matthew R., Zdenek, Christina N., Carter, Rebecca, Fry, Bryan G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529177/ https://www.ncbi.nlm.nih.gov/pubmed/34691069 http://dx.doi.org/10.3389/fimmu.2021.752442 |
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