Inhibition of GSK_3β by Iridoid Glycosides of Snowberry (Symphoricarpos albus) Effective in the Treatment of Alzheimer’s Disease Using Computational Drug Design Methods

The inhibition of glycogen synthase kinase-3β (GSK-3β) activity prevents tau hyperphosphorylation and binds it to the microtubule network. Therefore, a GSK-3β inhibitor may be a recommended drug for Alzheimer’s treatment. In silico methods are currently considered as one of the fastest and most cost...

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Detalles Bibliográficos
Autores principales: Eskandarzadeh, Marzieh, Kordestani-Moghadam, Parastou, Pourmand, Saeed, Khalili Fard, Javad, Almassian, Bijan, Gharaghani, Sajjad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529253/
https://www.ncbi.nlm.nih.gov/pubmed/34692636
http://dx.doi.org/10.3389/fchem.2021.709932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529253/
https://www.ncbi.nlm.nih.gov/pubmed/34692636
http://dx.doi.org/10.3389/fchem.2021.709932

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