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Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and P.1 Variants

The recent identification and rise to dominance of the P.1 and B.1.351 SARS-CoV-2 variants have brought international concern because they may confer fitness advantages. The same three positions in the receptor-binding domain (RBD) are affected in both variants, but where the 417 substitution differ...

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Detalles Bibliográficos
Autores principales: Bayarri-Olmos, Rafael, Jarlhelt, Ida, Johnsen, Laust Bruun, Hansen, Cecilie Bo, Helgstrand, Charlotte, Rose Bjelke, Jais, Matthiesen, Finn, Nielsen, Susanne Dam, Iversen, Kasper Karmark, Ostrowski, Sisse Rye, Bundgaard, Henning, Frikke-Schmidt, Ruth, Garred, Peter, Skjoedt, Mikkel-Ole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529273/
https://www.ncbi.nlm.nih.gov/pubmed/34691078
http://dx.doi.org/10.3389/fimmu.2021.757197