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Evaluation of Age-Dependent Immune Signatures in Patients With Multiple Sclerosis

BACKGROUND AND OBJECTIVES: In MS, an age-related decline in disease activity and a decreased efficacy of disease-modifying treatment have been linked to immunosenescence, a state of cellular dysfunction associated with chronic inflammation. METHODS: To evaluate age-related immunologic alterations in...

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Detalles Bibliográficos
Autores principales: Eschborn, Melanie, Pawlitzki, Marc, Wirth, Timo, Nelke, Christopher, Pfeuffer, Steffen, Schulte-Mecklenbeck, Andreas, Lohmann, Lisa, Rolfes, Leoni, Pape, Katrin, Eveslage, Maria, Bittner, Stefan, Gross, Catharina C., Ruck, Tobias, Wiendl, Heinz, Meuth, Sven G., Klotz, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529419/
https://www.ncbi.nlm.nih.gov/pubmed/34667129
http://dx.doi.org/10.1212/NXI.0000000000001094