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Sporadic Creutzfeldt-Jakob disease: Real-Time Quaking-Induced Conversion (RT-QuIC) assay represents a major diagnostic advance

Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare and fatal neurodegenerative disorder with an incidence of 1.5 to 2 cases per million population/year. The disease is caused by a proteinaceous infectious agent, named prion (or PrP(Sc)), which arises from the conformational conversion of the cellul...

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Detalles Bibliográficos
Autores principales: Cazzaniga, Federico Angelo, Bistaffa, Edoardo, De Luca, Chiara Maria Giulia, Indaco, Antonio, Bufano, Giuseppe, Giaccone, Giorgio, Moda, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529530/
https://www.ncbi.nlm.nih.gov/pubmed/34657408
http://dx.doi.org/10.4081/ejh.2021.3298