Apropos of Universal Epitope Discovery for COVID-19 Vaccines: A Framework for Targeted Phage Display-Based Delivery and Integration of New Evaluation Tools

Targeted bacteriophage (phage) particles are potentially attractive yet inexpensive platforms for immunization. Herein, we describe targeted phage capsid display of an immunogenically relevant epitope of the SARS-CoV-2 Spike protein that is empirically conserved, likely due to the high mutational co...

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Detalles Bibliográficos
Autores principales: Markosian, Christopher, Staquicini, Daniela I., Dogra, Prashant, Dodero-Rojas, Esteban, Tang, Fenny H. F., Smith, Tracey L., Contessoto, Vinícius G., Libutti, Steven K., Wang, Zhihui, Cristini, Vittorio, Whitford, Paul C., Burley, Stephen K., Onuchic, José N., Pasqualini, Renata, Arap, Wadih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529634/
https://www.ncbi.nlm.nih.gov/pubmed/34676381
http://dx.doi.org/10.1101/2021.08.30.458222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529634/
https://www.ncbi.nlm.nih.gov/pubmed/34676381
http://dx.doi.org/10.1101/2021.08.30.458222

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