Integrated single-cell and bulk RNA sequencing analysis identifies a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses in colorectal cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) contribute notably to colorectal cancer (CRC) tumorigenesis, stiffness, angiogenesis, immunosuppression and metastasis, and could serve as a promising therapeutic target. Our purpose was to construct CAF-related prognostic signature for CRC. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Hang, Liu, Heshu, Ge, Yang, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529760/
https://www.ncbi.nlm.nih.gov/pubmed/34670584
http://dx.doi.org/10.1186/s12935-021-02252-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529760/
https://www.ncbi.nlm.nih.gov/pubmed/34670584
http://dx.doi.org/10.1186/s12935-021-02252-9

Ejemplares similares