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Integrated single-cell and bulk RNA sequencing analysis identifies a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses in colorectal cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) contribute notably to colorectal cancer (CRC) tumorigenesis, stiffness, angiogenesis, immunosuppression and metastasis, and could serve as a promising therapeutic target. Our purpose was to construct CAF-related prognostic signature for CRC. METHODS:...

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Detalles Bibliográficos
Autores principales:	Zheng, Hang, Liu, Heshu, Ge, Yang, Wang, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529760/ https://www.ncbi.nlm.nih.gov/pubmed/34670584 http://dx.doi.org/10.1186/s12935-021-02252-9

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