Effects of dezocine on morphine tolerance and opioid receptor expression in a rat model of bone cancer pain

BACKGROUND: Clinically, the coadministration of opioids to enhance antinociception and decrease tolerance has attracted increasing research attention. We investigated the effects of dezocine, a mu- and kappa-opioid receptor agonist/antagonist, on morphine tolerance and explored the involvement of op...

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Detalles Bibliográficos
Autores principales: Wu, Lin-xin, Dong, Yan-peng, Zhu, Qian-mei, Zhang, Bo, Ai, Bo-lun, Yan, Tao, Zhang, Guo-hua, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529774/
https://www.ncbi.nlm.nih.gov/pubmed/34670518
http://dx.doi.org/10.1186/s12885-021-08850-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529774/
https://www.ncbi.nlm.nih.gov/pubmed/34670518
http://dx.doi.org/10.1186/s12885-021-08850-0

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