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Effects of dezocine on morphine tolerance and opioid receptor expression in a rat model of bone cancer pain

BACKGROUND: Clinically, the coadministration of opioids to enhance antinociception and decrease tolerance has attracted increasing research attention. We investigated the effects of dezocine, a mu- and kappa-opioid receptor agonist/antagonist, on morphine tolerance and explored the involvement of op...

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Detalles Bibliográficos
Autores principales:	Wu, Lin-xin, Dong, Yan-peng, Zhu, Qian-mei, Zhang, Bo, Ai, Bo-lun, Yan, Tao, Zhang, Guo-hua, Sun, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529774/ https://www.ncbi.nlm.nih.gov/pubmed/34670518 http://dx.doi.org/10.1186/s12885-021-08850-0

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