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A novel approach of recombinant laterosporulin production using the N-SH2 domain of SHP-2

BACKGROUND: The current study was aimed at evaluating the role of the N-SH2 domain of SHP-2 as a partner protein in the expression of a toxic peptide, laterosporulin (LTS). We also investigated its effects on the formation of the disulfide bond and functional folding of the peptide in vitro. The N-S...

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Detalles Bibliográficos
Autores principales: Salehzadeh, Simin, Tabatabaei, Mohammad, Derakhshandeh, Abdollah, Karbalaei-Heidari, Hamidreza, Kazemipour, Nasrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529825/
https://www.ncbi.nlm.nih.gov/pubmed/34674683
http://dx.doi.org/10.1186/s12896-021-00721-7