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Hotspot mutation profiles of AKT1 in Asian women with breast and endometrial cancers

BACKGROUND: The V-Akt murine thymoma viral oncogene (AKT) 1 (E17K) is a subfamily of serine/threonine protein kinases that affects the survival, proliferation, and invasion of cancer cells. The clinicopathological features and frequencies in Asian populations with AKT1 mutations in breast and endome...

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Detalles Bibliográficos
Autores principales: Shimoi, Tatsunori, Hashimoto, Jun, Sudo, Kazuki, Shimomura, Akihiko, Noguchi, Emi, Shimizu, Chikako, Yunokawa, Mayu, Yonemori, Kan, Yoshida, Hiroshi, Yoshida, Masayuki, Kato, Tomoyasu, Kinoshita, Takayuki, Fukuda, Takahiro, Fujiwara, Yasuhiro, Tamura, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529845/
https://www.ncbi.nlm.nih.gov/pubmed/34670536
http://dx.doi.org/10.1186/s12885-021-08869-3