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Enhanced IL-2 in early life limits the development of T(FH) and protective antiviral immunity

T follicular helper cell (T(FH))–dependent antibody responses are critical for long-term immunity. Antibody responses are diminished in early life, limiting long-term protective immunity and allowing prolonged or recurrent infection, which may be important for viral lung infections that are highly p...

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Detalles Bibliográficos
Autores principales: Pyle, Chloe J., Labeur-Iurman, Lucia, Groves, Helen T., Puttur, Franz, Lloyd, Clare M., Tregoning, John S., Harker, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529914/
https://www.ncbi.nlm.nih.gov/pubmed/34665220
http://dx.doi.org/10.1084/jem.20201555