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Partners in Crime: Beta-Cells and Autoimmune Responses Complicit in Type 1 Diabetes Pathogenesis

Type 1 diabetes (T1D) is an autoimmune disease characterized by autoreactive T cell-mediated destruction of insulin-producing pancreatic beta-cells. Loss of beta-cells leads to insulin insufficiency and hyperglycemia, with patients eventually requiring lifelong insulin therapy to maintain normal gly...

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Detalles Bibliográficos
Autores principales: Toren, Eliana, Burnette, KaLia S., Banerjee, Ronadip R., Hunter, Chad S., Tse, Hubert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529969/
https://www.ncbi.nlm.nih.gov/pubmed/34691077
http://dx.doi.org/10.3389/fimmu.2021.756548