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Functionally Mature CD1c(+) Dendritic Cells Preferentially Accumulate in the Inflammatory Arthritis Synovium

OBJECTIVE: To examine the role of synovial CD1c(+)DCs in patients with Inflammatory Arthritis (IA) with a specific focus on the transcriptional and maturation signatures that govern their function. METHODS: RNA sequencing was performed on healthy control (HC) peripheral blood (PB), IA PB, and IA syn...

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Detalles Bibliográficos
Autores principales: Canavan, Mary, Marzaioli, Viviana, Bhargava, Vipul, Nagpal, Sunil, Gallagher, Phil, Hurson, Conor, Mullan, Ronan, Veale, Douglas J., Fearon, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529992/
https://www.ncbi.nlm.nih.gov/pubmed/34691053
http://dx.doi.org/10.3389/fimmu.2021.745226