HOTTIP downregulation reduces neuronal damage and microglial activation in Parkinson's disease cell and mouse models

HOXA transcript at the distal tip (HOTTIP), a newly identified long noncoding RNA, has been shown to exhibit anti-inflammatory effects and inhibit oxygen-glucose deprivation-induced neuronal apoptosis. However, its role in Parkinson’s disease (PD) remains unclear. 1-Methyl-4-phenylpyridium (MPP(+))...

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Detalles Bibliográficos
Autores principales: Lun, Peng, Ji, Tao, Wan, De-Hong, Liu, Xia, Chen, Xiao-Dong, Yu, Shuai, Sun, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530116/
https://www.ncbi.nlm.nih.gov/pubmed/34472490
http://dx.doi.org/10.4103/1673-5374.322475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530116/
https://www.ncbi.nlm.nih.gov/pubmed/34472490
http://dx.doi.org/10.4103/1673-5374.322475

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