Substantial acetylcholine reduction in multiple brain regions of Mecp2-deficient female rats and associated behavioral abnormalities

Rett syndrome (RTT) is a neurodevelopmental disorder with X-linked dominant inheritance caused mainly by mutations in the methyl-CpG-binding protein 2 (MECP2) gene. The effects of various Mecp2 mutations have been extensively assessed in mouse models, but none adequately mimic the symptoms and patho...

Descripción completa

Detalles Bibliográficos
Autores principales: Murasawa, Hiroyasu, Kobayashi, Hiroyuki, Imai, Jun, Nagase, Takahiko, Soumiya, Hitomi, Fukumitsu, Hidefumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530288/
https://www.ncbi.nlm.nih.gov/pubmed/34673817
http://dx.doi.org/10.1371/journal.pone.0258830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530288/
https://www.ncbi.nlm.nih.gov/pubmed/34673817
http://dx.doi.org/10.1371/journal.pone.0258830

Ejemplares similares