Klotho deficiency intensifies hypoxia-induced expression of IFN-α/β through upregulation of RIG-I in kidneys

Hypoxia is a common pathway to the progression of end-stage kidney disease. Retinoic acid-inducible gene I (RIG-I) encodes an RNA helicase that recognizes viruses including SARS-CoV2, which is responsible for the production of interferon (IFN)-α/β to prevent the spread of viral infection. Recently,...

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Detalles Bibliográficos
Autores principales: Urabe, Asako, Doi, Shigehiro, Nakashima, Ayumu, Ike, Takeshi, Morii, Kenichi, Sasaki, Kensuke, Doi, Toshiki, Arihiro, Koji, Masaki, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530307/
https://www.ncbi.nlm.nih.gov/pubmed/34673800
http://dx.doi.org/10.1371/journal.pone.0258856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530307/
https://www.ncbi.nlm.nih.gov/pubmed/34673800
http://dx.doi.org/10.1371/journal.pone.0258856

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