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Proximal-end bias from in-vitro reconstituted nucleosomes and the result on downstream data analysis
The most basic level of eukaryotic gene regulation is the presence or absence of nucleosomes on DNA regulatory elements. In an effort to elucidate in vivo nucleosome patterns, in vitro studies are frequently used. In vitro, short DNA fragments are more favorable for nucleosome formation, increasing...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530345/ https://www.ncbi.nlm.nih.gov/pubmed/34673804 http://dx.doi.org/10.1371/journal.pone.0258737 |