Proximal-end bias from in-vitro reconstituted nucleosomes and the result on downstream data analysis

The most basic level of eukaryotic gene regulation is the presence or absence of nucleosomes on DNA regulatory elements. In an effort to elucidate in vivo nucleosome patterns, in vitro studies are frequently used. In vitro, short DNA fragments are more favorable for nucleosome formation, increasing...

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Detalles Bibliográficos
Autores principales: Bates, David A., Bates, Charles E., Earl, Andrew S., Skousen, Colin, Fetbrandt, Ashley N., Ritchie, Jordon, Bodily, Paul M., Johnson, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530345/
https://www.ncbi.nlm.nih.gov/pubmed/34673804
http://dx.doi.org/10.1371/journal.pone.0258737

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