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Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis

Research in schizophrenia (SZ) emphasizes the need for new therapeutic approaches based on antioxidant/anti-inflammatory compounds and psycho-social therapy. A hallmark of SZ is a dysfunction of parvalbumin-expressing fast-spiking interneurons (PVI), which are essential for neuronal synchrony during...

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Detalles Bibliográficos
Autores principales: Dwir, Daniella, Cabungcal, Jan-Harry, Xin, Lijing, Giangreco, Basilio, Parietti, Enea, Cleusix, Martine, Jenni, Raoul, Klauser, Paul, Conus, Philippe, Cuénod, Michel, Steullet, Pascal, Do, Kim Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530393/
https://www.ncbi.nlm.nih.gov/pubmed/34080015
http://dx.doi.org/10.1093/schbul/sbab066