Cargando…

β-Amyloid disruption of LTP/LTD balance is mediated by AKAP150-anchored PKA and Calcineurin regulation of Ca(2+)-permeable AMPA receptors

Regulated insertion and removal of postsynaptic AMPA glutamate receptors (AMPARs) mediates hippocampal long-term potentiation (LTP) and long-term depression (LTD) synaptic plasticity underlying learning and memory. In Alzheimer’s disease β-amyloid (Aβ) oligomers may impair learning and memory by alt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sanderson, Jennifer L., Freund, Ronald K., Gorski, Jessica A., Dell’Acqua, Mark L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530450/ https://www.ncbi.nlm.nih.gov/pubmed/34610314 http://dx.doi.org/10.1016/j.celrep.2021.109786

Ejemplares similares

AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca(2+)-Permeable AMPA Receptors to Control LTP
por: Purkey, Alicia M., et al.
Publicado: (2018)

A calcineurin/AKAP complex is required for NMDA receptor-dependent LTD
por: Jurado, Sandra, et al.
Publicado: (2010)

AKAP79/150 coordinates leptin-induced PKA signaling to regulate K(ATP) channel trafficking in pancreatic β-cells
por: Cochrane, Veronica A., et al.
Publicado: (2021)

Balanced interactions of calcineurin with AKAP79 regulate Ca(2+)–calcineurin–NFAT signaling
por: Li, Huiming, et al.
Publicado: (2012)

PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
por: Park, Pojeong, et al.
Publicado: (2021)

Proteasomal-Mediated Degradation of AKAP150 Accompanies AMPAR Endocytosis during cLTD
por: Cheng, Wenwen, et al.
Publicado: (2020)

DHHC2 regulates fear memory formation, LTP, and AKAP150 signaling in the hippocampus
por: Li, Meng-Die, et al.
Publicado: (2023)

Engineering a memory with LTD and LTP
por: Nabavi, Sadegh, et al.
Publicado: (2014)

Induction of β-adrenergic metaplasticity of LTP requires intact anchoring of PKA
por: Hoffman, Janlyn R., et al.
Publicado: (2019)

AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency
por: Gold, Matthew G, et al.
Publicado: (2012)

Phosphorylation-Dependent Regulation of Ca(2+)-Permeable AMPA Receptors During Hippocampal Synaptic Plasticity
por: Purkey, Alicia M., et al.
Publicado: (2020)

LTP or LTD? Modeling the Influence of Stress on Synaptic Plasticity
por: Peters, Achim, et al.
Publicado: (2018)

Molecular evolution of a-kinase anchoring protein (AKAP)-7: implications in comparative PKA compartmentalization
por: Johnson, Keven R, et al.
Publicado: (2012)

AKAP79/150 recruits the transcription factor NFAT to regulate signaling to the nucleus by neuronal L-type Ca(2+) channels
por: Murphy, Jonathan G., et al.
Publicado: (2019)

How bursting and tonic dopaminergic activity generates LTP and LTD
por: Thompson, Adedoyin, et al.
Publicado: (2007)

Glutamate Transporters in Hippocampal LTD/LTP: Not Just Prevention of Excitotoxicity
por: Gonçalves-Ribeiro, Joana, et al.
Publicado: (2019)

PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation
por: Radeva, Mariya Y., et al.
Publicado: (2014)

Secreted Amyloid Precursor Protein-Alpha Enhances LTP Through the Synthesis and Trafficking of Ca(2+)-Permeable AMPA Receptors
por: Livingstone, Rhys W., et al.
Publicado: (2021)

Curcumin Protects Neurons from Glutamate-Induced Excitotoxicity by Membrane Anchored AKAP79-PKA Interaction Network
por: Chen, Kui, et al.
Publicado: (2015)

Homer1 gene products orchestrate Ca(2+)-permeable AMPA receptor distribution and LTP expression
por: Rozov, Andrei, et al.
Publicado: (2012)

Dissociation between AKAP3 and PKA(RII) Promotes AKAP3 Degradation in Sperm Capacitation
por: Hillman, Pnina, et al.
Publicado: (2013)

CaMKII holoenzyme mechanisms that govern the LTP versus LTD decision
por: Cook, Sarah G., et al.
Publicado: (2021)

Mechanism of Neuroprotective Mitochondrial Remodeling by PKA/AKAP1
por: Merrill, Ronald A., et al.
Publicado: (2011)

PKA, PKC, and AKAP localization in and around the neuromuscular junction
por: Perkins, Guy A, et al.
Publicado: (2001)

Calcineurin Mediates Synaptic Scaling Via Synaptic Trafficking of Ca(2+)-Permeable AMPA Receptors
por: Kim, Seonil, et al.
Publicado: (2014)

PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome
por: Terrin, Anna, et al.
Publicado: (2012)

Compartmentalization Role of A-Kinase Anchoring Proteins (AKAPs) in Mediating Protein Kinase A (PKA) Signaling and Cardiomyocyte Hypertrophy
por: Rababa’h, Abeer, et al.
Publicado: (2014)

The modular cross-synaptic nature of LTP/LTD following on-going neural activity
por: Loebel, Alex, et al.
Publicado: (2011)

Spatial Object Recognition Enables Endogenous LTD that Curtails LTP in the Mouse Hippocampus
por: Goh, Jinzhong Jeremy, et al.
Publicado: (2013)

Stable reinforcement learning via temporal competition between LTP and LTD traces
por: Huertas, Marco A, et al.
Publicado: (2014)

Bidirectional and long-lasting control of alcohol-seeking behavior by corticostriatal LTP and LTD
por: Ma, Tengfei, et al.
Publicado: (2018)

The effect of LTP- and LTD-like visual stimulation on modulation of human orientation discrimination
por: Marzoll, Andreas, et al.
Publicado: (2018)

Highly Functionalized Terpyridines as Competitive Inhibitors of AKAP–PKA Interactions**
por: Schäfer, Gesa, et al.
Publicado: (2013)

Postsynaptic Synaptotagmins Mediate AMPA Receptor Exocytosis During LTP
por: Wu, Dick, et al.
Publicado: (2017)

The Ca(V)1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca(2+) channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome
por: Sanderson, Jennifer L., et al.
Publicado: (2022)

Metaplastic LTP inhibition after LTD induction in CA1 hippocampal slices involves NMDA Receptor-mediated Neurosteroidogenesis
por: Izumi, Yukitoshi, et al.
Publicado: (2013)

Induction and binary expression of LTP/LTD in a minimal model of the CaMKII system
por: Graupner, Michael, et al.
Publicado: (2007)

Brownian diffusion of AMPA receptors is sufficient to explain fast onset of LTP
por: Tolle, Dominic P, et al.
Publicado: (2010)

Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP
por: Cho, Eunsil, et al.
Publicado: (2015)

Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors
por: Penn, A.C., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s23sejt4dh8dh7l6i2ucc1q9jj