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Stretching of the retinal pigment epithelium contributes to zebrafish optic cup morphogenesis

The vertebrate eye primordium consists of a pseudostratified neuroepithelium, the optic vesicle (OV), in which cells acquire neural retina or retinal pigment epithelium (RPE) fates. As these fates arise, the OV assumes a cup shape, influenced by mechanical forces generated within the neural retina....

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Detalles Bibliográficos
Autores principales: Moreno-Mármol, Tania, Ledesma-Terrón, Mario, Tabanera, Noemi, Martin-Bermejo, Maria Jesús, Cardozo, Marcos J, Cavodeassi, Florencia, Bovolenta, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530511/
https://www.ncbi.nlm.nih.gov/pubmed/34545806
http://dx.doi.org/10.7554/eLife.63396