Integrated evaluation of telomerase activation and telomere maintenance across cancer cell lines

In cancer, telomere maintenance is critical for the development of replicative immortality. Using genome sequences from the Cancer Cell Line Encyclopedia and Genomics of Drug Sensitivity in Cancer Project, we calculated telomere content across 1299 cancer cell lines. We find that telomerase reverse...

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Detalles Bibliográficos
Autores principales: Hu, Kevin, Ghandi, Mahmoud, Huang, Franklin W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530513/
https://www.ncbi.nlm.nih.gov/pubmed/34486523
http://dx.doi.org/10.7554/eLife.66198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530513/
https://www.ncbi.nlm.nih.gov/pubmed/34486523
http://dx.doi.org/10.7554/eLife.66198

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