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Collective regulation of chromatin modifications predicts replication timing during cell cycle

Replication timing (RT) associates with genome architecture, while having a mixed relationship to histone marks. By profiling replication at high resolution and assessing broad histone marks across the cell cycle at the resolution of RT with and without genetic perturbation, we address the causal re...

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Detalles Bibliográficos
Autores principales: Van Rechem, Capucine, Ji, Fei, Chakraborty, Damayanti, Black, Joshua C., Sadreyev, Ruslan I., Whetstine, Johnathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530517/
https://www.ncbi.nlm.nih.gov/pubmed/34610305
http://dx.doi.org/10.1016/j.celrep.2021.109799