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A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer

Platinum-based chemotherapy remains widely used in advanced non-small cell lung cancer (NSCLC) despite experimental evidence of its potential to induce long-term detrimental effects, including the promotion of pro-metastatic microenvironments. In this study, we investigated the interconnected pathwa...

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Detalles Bibliográficos
Autores principales: Bertolini, Giulia, Cancila, Valeria, Milione, Massimo, Lo Russo, Giuseppe, Fortunato, Orazio, Zaffaroni, Nadia, Tortoreto, Monica, Centonze, Giovanni, Chiodoni, Claudia, Facchinetti, Federica, Pollaci, Giuliana, Taiè, Giulia, Giovinazzo, Francesca, Moro, Massimo, Camisaschi, Chiara, De Toma, Alessandro, D’Alterio, Crescenzo, Pastorino, Ugo, Tripodo, Claudio, Scala, Stefania, Sozzi, Gabriella, Roz, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530918/
https://www.ncbi.nlm.nih.gov/pubmed/34023505
http://dx.doi.org/10.1016/j.ymthe.2021.05.014