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LGR6 activates the Wnt/β-catenin signaling pathway and forms a β-catenin/TCF7L2/LGR6 feedback loop in LGR6(high) cervical cancer stem cells

The leucine-rich repeat-containing G-protein-coupled receptor 6 (LGR6) is considered to be a stem cell marker in many normal tissues and promotes tissue development, regeneration, and repair. LGR6 is also related to the initiation and progression of some malignant tumors. However, the role of LGR6 i...

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Detalles Bibliográficos
Autores principales: Feng, Qian, Li, Shan, Ma, Hong-Mei, Yang, Wen-Ting, Zheng, Peng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8530990/
https://www.ncbi.nlm.nih.gov/pubmed/34489551
http://dx.doi.org/10.1038/s41388-021-02002-1