Novel HLA-B7-restricted human metapneumovirus epitopes enhance viral clearance in mice and are recognized by human CD8(+) T cells

Human metapneumovirus (HMPV) is a leading cause of acute lower respiratory tract illness in children and adults. Repeated infections are common and can be severe in young, elderly, and immunocompromised persons due to short-lived protective humoral immunity. In turn, few protective T cell epitopes h...

Descripción completa

Detalles Bibliográficos
Autores principales: Miranda-Katz, Margot, Erickson, John J., Lan, Jie, Ecker, Alwyn, Zhang, Yu, Joyce, Sebastian, Williams, John V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531189/
https://www.ncbi.nlm.nih.gov/pubmed/34675220
http://dx.doi.org/10.1038/s41598-021-00023-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531189/
https://www.ncbi.nlm.nih.gov/pubmed/34675220
http://dx.doi.org/10.1038/s41598-021-00023-0

Ejemplares similares