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Pharmacokinetics and Drug-Drug Interactions of Abacavir and Lamuvudine Co-administered With Antituberculosis Drugs in HIV-Positive Children Treated for Multidrug-Resistant Tuberculosis

Given the high prevalence of multidrug-resistant (MDR)-TB in high HIV burden settings, it is important to identify potential drug-drug interactions between MDR-TB treatment and widely used nucleoside reverse transcriptase inhibitors (NRTIs) in HIV-positive children. Population pharmacokinetic models...

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Detalles Bibliográficos
Autores principales: van der Laan, Louvina E., Garcia-Prats, Anthony J., Schaaf, H. Simon, Winckler, Jana L., Draper, Heather, Norman, Jennifer, Wiesner, Lubbe, McIlleron, Helen, Denti, Paolo, Hesseling, Anneke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531271/
https://www.ncbi.nlm.nih.gov/pubmed/34690765
http://dx.doi.org/10.3389/fphar.2021.722204