Steroid sulfatase deficiency causes cellular senescence and abnormal differentiation by inducing Yippee-like 3 expression in human keratinocytes

Human steroid sulfatase (STS) is an enzyme that catalyzes the hydrolysis of dehydroepiandrosterone sulfate (DHEAS), estrone sulfate (E1S), and cholesterol sulfate. Abnormal expression of STS causes several diseases including colorectal, breast, and prostate cancer and refractory skin disease. In par...

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Detalles Bibliográficos
Autores principales: Baek, Hyoung-Seok, Kwon, Tae-Uk, Shin, Sangyun, Kwon, Yeo-Jung, Chun, Young-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531280/
https://www.ncbi.nlm.nih.gov/pubmed/34675221
http://dx.doi.org/10.1038/s41598-021-00051-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531280/
https://www.ncbi.nlm.nih.gov/pubmed/34675221
http://dx.doi.org/10.1038/s41598-021-00051-w

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