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Single-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progression
Breast cancer stem-like cells (BCSCs) play vital roles in tumorigenesis and progression. However, the origin and dynamic changes of BCSCs are still to be elucidated. Using the breast cancer mouse model MMTV-PyMT, we constructed a single-cell atlas of 31,778 cells from four distinct stages of tumor p...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artigo Texto |
| Idioma: | English |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531288/ https://www.ncbi.nlm.nih.gov/pubmed/34675206 http://dx.doi.org/10.1038/s41419-021-04261-y |