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Single-cell transcriptomics reveal the heterogeneity and dynamic of cancer stem-like cells during breast tumor progression

Breast cancer stem-like cells (BCSCs) play vital roles in tumorigenesis and progression. However, the origin and dynamic changes of BCSCs are still to be elucidated. Using the breast cancer mouse model MMTV-PyMT, we constructed a single-cell atlas of 31,778 cells from four distinct stages of tumor p...

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Detalles Bibliográficos
Autores principales: Jiang, Guojuan, Tu, Juchuanli, Zhou, Lei, Dong, Mengxue, Fan, Jue, Chang, Zhaoxia, Zhang, Lixing, Bian, Xiuwu, Liu, Suling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531288/
https://www.ncbi.nlm.nih.gov/pubmed/34675206
http://dx.doi.org/10.1038/s41419-021-04261-y