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Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins

Owing to their morphological complexity and dense network connections, neurons modify their proteomes locally, using mRNAs and ribosomes present in the neuropil (tissue enriched for dendrites and axons). Although ribosome biogenesis largely takes place in the nucleus and perinuclear region, neuronal...

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Detalles Bibliográficos
Autores principales: Fusco, Claudia M., Desch, Kristina, Dörrbaum, Aline R., Wang, Mantian, Staab, Anja, Chan, Ivy C. W., Vail, Eleanor, Villeri, Veronica, Langer, Julian D., Schuman, Erin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531293/
https://www.ncbi.nlm.nih.gov/pubmed/34675203
http://dx.doi.org/10.1038/s41467-021-26365-x