The intronic branch point sequence is under strong evolutionary constraint in the bovine and human genome

The branch point sequence is a cis-acting intronic motif required for mRNA splicing. Despite their functional importance, branch point sequences are not routinely annotated. Here we predict branch point sequences in 179,476 bovine introns and investigate their variability using a catalogue of 29.4 m...

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Detalles Bibliográficos
Autores principales: Kadri, Naveen Kumar, Mapel, Xena Marie, Pausch, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531310/
https://www.ncbi.nlm.nih.gov/pubmed/34675361
http://dx.doi.org/10.1038/s42003-021-02725-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531310/
https://www.ncbi.nlm.nih.gov/pubmed/34675361
http://dx.doi.org/10.1038/s42003-021-02725-7

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