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Dual recombinase action in the normal and neoplastic mammary gland epithelium

We developed a transgenic mouse line that expresses the codon-optimized Flp recombinase under the control of the MMTV promoter in luminal epithelial cells of the mammary gland. In this report, we demonstrate the versatile applicability of the new MMTV-Flp strain to manipulate genes in a temporally a...

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Detalles Bibliográficos
Autores principales: Rädler, Patrick D., Vistisen, Kerry, Triplett, Aleata A., Dennaoui, Rayane, Li, Yong, Shrestha, Hridaya, Ferraiuolo, Rosa-Maria, Thangasamy, Amalraj, Saur, Dieter, Wagner, Kay-Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531329/
https://www.ncbi.nlm.nih.gov/pubmed/34675248
http://dx.doi.org/10.1038/s41598-021-00231-8