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Dual recombinase action in the normal and neoplastic mammary gland epithelium
We developed a transgenic mouse line that expresses the codon-optimized Flp recombinase under the control of the MMTV promoter in luminal epithelial cells of the mammary gland. In this report, we demonstrate the versatile applicability of the new MMTV-Flp strain to manipulate genes in a temporally a...
Autores principales: | Rädler, Patrick D., Vistisen, Kerry, Triplett, Aleata A., Dennaoui, Rayane, Li, Yong, Shrestha, Hridaya, Ferraiuolo, Rosa-Maria, Thangasamy, Amalraj, Saur, Dieter, Wagner, Kay-Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531329/ https://www.ncbi.nlm.nih.gov/pubmed/34675248 http://dx.doi.org/10.1038/s41598-021-00231-8 |
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