Multi-tissue transcriptome-wide association study identifies eight candidate genes and tissue-specific gene expression underlying endometrial cancer susceptibility

Genome-wide association studies (GWAS) have revealed sixteen risk loci for endoemtrial cancer but the identification of candidate susceptibility genes remains challenging. Here, we perform transcriptome-wide association study (TWAS) analyses using the largest endometrial cancer GWAS and gene express...

Descripción completa

Detalles Bibliográficos
Autores principales: Kho, Pik Fang, Wang, Xuemin, Cuéllar-Partida, Gabriel, Dörk, Thilo, Goode, Ellen L., Lambrechts, Diether, Scott, Rodney J., Spurdle, Amanda B., O’Mara, Tracy A., Glubb, Dylan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531339/
https://www.ncbi.nlm.nih.gov/pubmed/34675350
http://dx.doi.org/10.1038/s42003-021-02745-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531339/
https://www.ncbi.nlm.nih.gov/pubmed/34675350
http://dx.doi.org/10.1038/s42003-021-02745-3

Ejemplares similares