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Mechanisms of Rhizoma Coptidis against type 2 diabetes mellitus explored by network pharmacology combined with molecular docking and experimental validation

This study systematically explored the underlying mechanism of Rhizoma Coptidis against type 2 diabetes mellitus (T2DM) by using network pharmacology and molecular docking and experimental validation. We retrieved and screened active compounds of Rhizoma Coptidis and corresponding T2DM-related targe...

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Detalles Bibliográficos
Autores principales: An, Wenrong, Huang, Yanqin, Chen, Shouqiang, Teng, Tao, Shi, Yingning, Sun, Zhenhai, Xu, Yunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531350/
https://www.ncbi.nlm.nih.gov/pubmed/34675276
http://dx.doi.org/10.1038/s41598-021-00293-8