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Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients
Cancer is the leading cause of death in the geriatric dog population. Currently, the use of immune checkpoint inhibitors (ICIs) such as anti-CTLA4 antibodies has markedly improved the prognosis of several cancers in their advanced stages. However, ICIs targeting CTLA4 blockade to treat canine cancer...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8531395/ https://www.ncbi.nlm.nih.gov/pubmed/34675296 http://dx.doi.org/10.1038/s41598-021-00325-3 |